Faculty of Biology - Biotechnology - Âé¶¹´«Ã½ Where the passion of science is nurtured and empowered Thu, 14 May 2026 08:35:10 +0000 vi hourly 1 /wp-content/uploads/2022/07/cropped-Alumi-event-02-32x32.png Faculty of Biology - Biotechnology - Âé¶¹´«Ã½ 32 32 [VNUHCM S&T PROJECT EVALUATION] DEVELOPING SMALL-DIAMETER VASCULAR GRAFTS /institutional-evaluation-and-acceptance-of-national-level-research-project-on-developing-small-diameter-vascular-grafts/ /institutional-evaluation-and-acceptance-of-national-level-research-project-on-developing-small-diameter-vascular-grafts/#respond Fri, 31 Oct 2025 11:32:34 +0000 /?p=23032

On 31 October, the VNUHCM Scientific and Technological Project Evaluation Council convened at VNUHCM–Âé¶¹´«Ã½ (HCMUS) to review the outcomes of a VNUHCM-level applied research and technology development project entitled “Research into Developing Small-Diameter Vascular Grafts Using a Bioreactor System for Application in Vascular Grafting.†The project is led by Assoc. Prof. Trần Lê Bảo Hà, a lecturer at HCMUS.

This project falls under the Programme for Fundamental Science Development in Chemistry, Life Sciences, Earth Sciences, and Marine Sciences for the 2017–2025 period (Programme 562), with HCMUS as the primary implementing institution.

During the implementation process, the research team achieved significant results. The project identified porcine carotid arteries and human umbilical arteries as two potential raw materials for fabricating small-diameter vascular grafts, simultaneously optimising the bioreactor system to regenerate vascular cells under near-physiological conditions. By combining physical and chemical agents in the decellularisation process, the team successfully created suitable acellular vascular scaffolds for mechanical reinforcement. Surface treatment steps using heparin bonding significantly improved anti-coagulation capability and cell adhesion. Notably, the project established a standard evaluation framework for vascular grafts comprising 18 criteria. Testing on animal models showed that the grafts maintained stable blood flow and did not form thrombi after three months, confirming the feasibility and potential application of this research direction.

Assoc. Prof. Trần Lê Bảo Hà, Project Leader, presenting the project’s research content and outcomes to the Evaluation Council.

Beyond the specialised results, the project yielded substantial outcomes in scientific publications and training: four international SCIE articles and four domestic articles were published; three Type I products, two procedures, and two reports (Type II products) were completed; the project fully trained three Master’s students and supported two PhD research students (Type III products); and one intellectual property registration application was formally accepted.

The VNUHCM Scientific and Technological Project Evaluation Council concluded that the project fully completed all contents and products as specified in the proposal. The quality and quantity of registered products, as well as the applicability, met the requirements, with the publication and postgraduate training results being rated excellent. The Council unanimously recommended that the research team continue to finalise the documentation and report for submission for evaluation and acceptance at the higher, national level in the near future. This marks an important step forward in the study of biomaterials for regenerative medicine, contributing to affirming the scientific and technological capacity of HCMUS in the interdisciplinary research field spanning biology, materials science, and biomedical technology.

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VNUHCM-UNIVERSITY OF SCIENCE FORMALLY CONVENES STRATEGIC DIALOGUE WITH NATIONAL CHUNG HSING UNIVERSITY (TAIWAN) /22916-2/ /22916-2/#respond Fri, 24 Oct 2025 05:02:19 +0000 /?p=22916

On 24 October, VNUHCM-Âé¶¹´«Ã½ (HCMUS) convened a strategic meeting with a delegation from National Chung Hsing University (NCHU, Taiwan) to fortify academic cooperation, focusing specifically upon agriculture, biology, and environmental engineering.

The visiting delegation comprised Mr Wei-Chih Lin – Director of the Education Division at the Taipei Economic and Cultural Office in Ho Chi Minh City (TECO), alongside distinguished faculty members from NCHU. Representing HCMUS were Dr Võ Hồng Hải – Deputy Head of the Office of External Relations, and senior academic staff from the Faculties of Biology – Biotechnology, Chemistry, and Physics – Engineering Physics.

During the proceedings, HCMUS representatives presented an overview of the university’s academic curricula and research infrastructure, underscoring key competencies in biotechnology, notably plant physiology and biochemistry, microbial technology, cell technology, and biosensing. Reciprocally, representatives from NCHU delineated academic initiatives and technological priorities, encompassing smart agriculture, bio-industrial mechatronics, veterinary science, and animal science. The parties identified the application of artificial intelligence in crop management and livestock health diagnostics as a primary domain for potential collaboration.

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Representatives from VNUHCM-Âé¶¹´«Ã½ and National Chung Hsing University (Taiwan) engaging in substantive dialogue regarding collaboration in biotechnology, smart agriculture, and applied research innovation.

The two institutions explored avenues for strategic partnership regarding sustainable agricultural biotechnology, the development of climate-resilient crops, plant-based biotherapeutics, and automation technologies for modern farming systems. Participants advanced proposals to facilitate academic exchanges for researchers, lecturers, and students, and to interconnect laboratory facilities in support of large-scale joint research initiatives.

This meeting underscored the synergistic potential between the foundational scientific strengths of HCMUS and the applied technological expertise held by NCHU. Both parties reached a consensus to establish a long-term cooperative framework aimed at advancing international academic engagement, developing high-quality human capital, and fostering innovation within biotechnology and high-tech agriculture.

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[DOCTORAL THESIS DEFENCE] DOCTORAL RESEARCHER LÊ HỒNG LINH SUCCESSFULLY DEFENDS DOCTORAL THESIS IN BIOLOGY – BIOTECHNOLOGY /researcher-le-hong-linh-successfully-defends-doctoral-dissertation-in-biology-biotechnology/ /researcher-le-hong-linh-successfully-defends-doctoral-dissertation-in-biology-biotechnology/#respond Wed, 22 Oct 2025 04:20:59 +0000 /?p=22670

On October 21, at the VNUHCM-Âé¶¹´«Ã½ (HCMUS), Researcher Lê Hồng Linh successfully defended the doctoral thesis titled ‘Study on the Preparation and Testing of a Biological Product Using Yeast Cell Surface Technology (Saccharomyces cerevisiae) for the Prevention of White Spot Syndrome Virus (WSSV) in Whiteleg Shrimp (Litopenaeus vannamei),’Ìýunder the supervision of Prof. Äặng Thị Phương Thảo.

The dissertation substantiated the significant biological efficacy of the Saccharomyces cerevisiae W303::vp28 extract in stimulating immune responses and enhancing resistance against white spot disease in whiteleg shrimp. Supplementation of 10 g of yeast extract per kilogram of feed resulted in a protection rate against WSSV of 87.19 ± 2.15% after 14 days.

Based on these findings, the researcher developed an optimized formulation combining 50% yeast extract containing VP28 and 50% beneficial microorganisms (density 109 cfu/g). The study determined the optimal application method as a daily feed supplement of 10 g of biological product per kilogram of feed, a protocol that improved both shrimp growth and disease resistance.

Laboratory trials confirmed that the completed formulation achieved a protection rate of 77.8 ± 1.9% against WSSV and enhanced shrimp immunity. Enzyme activity levels of SOP reached 61 ± 1 and PO reached 2.2 ± 0.1—markedly higher than treatments using only probiotic supplements (SOP: 34 ± 1.2; PO: 1.5 ± 0.1) or industrial feed alone (SOP: 25 ±1; PO: 1.1 ± 0.1).

Doctoral researcher Lê Hồng Linh presenting the doctoral thesis before the Examination Committee.

Field trials conducted at commercial shrimp ponds in Binh Dinh Province demonstrated the most significant impact of the study. The product exhibited a dual effect: boosting shrimp immune system activity throughout the cultivation period and concurrently improving pond water quality by controlling H2S gas, reducing NH3 and COD concentrations, and inhibiting Vibrio spp. proliferation.

After 90 days of cultivation, shrimp raised in ponds treated with the new formulation achieved an average weight of 16.02 ± 0.37 g (an 18.2% increase) and a length of 12.54 ± 0.29 cm (a 6.6% increase) compared to the control group. From an economic perspective, the trial pond yielded a profit of VND 129.7 million, approximately 1.6 times higher than ponds utilizing existing commercial products. The yeast extract–probiotic formulation demonstrated strong potential for practical application in shrimp aquaculture by enhancing immune function, reducing disease incidence, and improving profitability for farmers.

The Examination Committee and doctoral researcher Lê Hồng Linh at HCMUS.

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